| 產(chǎn)品編號(hào) | bs-21162R-BF488 |
| 英文名稱 | Rabbit Anti-RASGEF1B/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的RASGEF1B蛋白抗體 |
| 別 名 | GPIG4. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Pig, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 55kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RASGEF1B |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: RASGEF1B (RasGEF Domain Family Member 1B) is a Protein Coding gene. Diseases associated with RASGEF1B include Chromosome 4Q21 Deletion Syndrome. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1C. Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro). Subunit: Interacts with Ras family proteins (By similarity). Interacts with CCDC124 during cytokinesis. DISEASE: Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS). Similarity: Contains 1 N-terminal Ras-GEF domain. Contains 1 Ras-GEF domain. Database links: Entrez Gene: 153020 Human SwissProt: Q0VAM2 Human Unigene: 591696 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
