產(chǎn)品編號(hào) | bs-12768R-BF488 |
英文名稱 | Rabbit Anti-VPS26/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的液泡蛋白分選蛋白26抗體 |
別 名 | FLJ12930; HB 58; HB58; Hbeta 58; Hbeta 58 homolog; Hbeta58; Hbeta58 homolog; hVPS 26; hVPS26; MGC94168; PEP 8A; PEP8A; Vacuolar protein sorting 26 A; Vacuolar protein sorting 26; Vacuolar protein sorting 26 homolog A; Vacuolar protein sorting 26 homolog A S. pombe; Vacuolar protein sorting 26 homolog A yeast; Vacuolar protein sorting 26 yeast; Vacuolar protein sorting 26 yeast homolog; Vacuolar protein sorting 26A; Vacuolar protein sorting associated protein 26A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26; Vesicle protein sorting 26A; VP26A_HUMAN; VPS 26; VPS 26A; VPS26A. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 淋巴細(xì)胞 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 38kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human VPS26 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Subcellular Location: Cytoplasm. Endosome membrane. Similarity: Belongs to the VPS26 family. Database links: Entrez Gene: 9559 Human Entrez Gene: 30930 Mouse Omim: 605506 Human SwissProt: O75436 Human SwissProt: P40336 Mouse Unigene: 499925 Human Unigene: 260703 Mouse Unigene: 473468 Mouse Unigene: 3673 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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