| 產(chǎn)品編號(hào) | bs-19861R-BF488 |
| 英文名稱 | Rabbit Anti-RGS3/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子3抗體 |
| 別 名 | C2PA; FLJ20370; FLJ31516; FLJ90496; PDZ RGS 3; PDZ RGS3; Regulator of G protein signaling 3; Regulator of G protein signalling 3; Regulator of G-protein signaling 3; RGP 3; RGP3; RGS 3; RGS3; RGS3_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 132kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RGS3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases. Subcellular Location: Cytoplasm. Nucleus. Cell membrane. Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear. Post-translational modifications: Phosphorylated by cyclic GMP-dependent protein kinase. ISGylated. Similarity: Contains 1 C2 domain. Contains 1 PDZ (DHR) domain. Contains 1 RGS domain. Database links: Entrez Gene: 5998 Human Entrez Gene: 50780 Mouse Omim: 602189 Human SwissProt: P49796 Human SwissProt: Q9DC04 Mouse Unigene: 494875 Human Unigene: 286753 Mouse Unigene: 53900 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
