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Rabbit Anti-N4BP2/RBITC Conjugated antibody (bs-18985R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18985R-RBITC
英文名稱 Rabbit Anti-N4BP2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的E3泛素連接酶NEDD4結合蛋白2抗體
別    名 B3BP; BCL 3 binding protein; BCL3 binding protein; FLJ10680; KIAA1413; Nedd4 binding protein 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 199kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human N4BP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq, Jul 2008]

Function:
Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.

Subunit:
Binds NEDD4 By similarity. Binds BCL3 and CREBBP.

Subcellular Location:
Cytoplasm

Post-translational modifications:
Ubiquitinated; this targets the protein for degradation by the proteasome

Similarity:
Contains 1 CUE domain.
Contains 1 Smr domain.

Database links:

Entrez Gene: 55728 Human

SwissProt: Q86UW6 Human

Unigene: 396494 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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