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Rabbit Anti-LIN9/BF488 Conjugated antibody (bs-18283R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-18283R-BF488
英文名稱 Rabbit Anti-LIN9/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的LIN9蛋白抗體
別    名 BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  細(xì)胞周期蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIN9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Function:
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.

Subcellular Location:
Nucleus > nucleoplasm. Found in perinucleolar structures. Associated with chromatin.

Tissue Specificity:
Expressed in thymus and testis.

Similarity:
Belongs to the lin-9 family.

Database links:

Entrez Gene: 286826 Human

Entrez Gene: 421316 Chicken

Entrez Gene: 72568 Mouse

Entrez Gene: 689523 Rat

Entrez Gene: 323027 Zebrafish

Entrez Gene: 560867 Zebrafish

Omim: 609375 Human

SwissProt: Q5TKA1 Human

SwissProt: Q8C735 Mouse

SwissProt: Q5RHQ8 Zebrafish

Unigene: 120817 Human

Unigene: 275044 Mouse

Unigene: 214693 Rat

Unigene: 76676 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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