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Rabbit Anti-KIF2A/Cy5 Conjugated antibody (bs-17055R-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17055R-Cy5
英文名稱 Rabbit Anti-KIF2A/Cy5 Conjugated antibody
中文名稱 Cy5標記的驅動蛋白家族成員2A抗體
別    名 HK2; kif2; Kif2a; KIF2A_HUMAN; Kinesin 2; Kinesin heavy chain 2; Kinesin heavy chain member 2; Kinesin heavy chain member 2A; Kinesin like protein KIF2A; Kinesin-2; Kinesin-like protein KIF2A; kns2; M Kinesin; M-Kinesin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF2A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.

Subcellular Location:
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.

Similarity:
Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 3796 Human

Entrez Gene: 16563 Mouse

Entrez Gene: 84391 Rat

Omim: 602591 Human

SwissProt: O00139 Human

SwissProt: P28740 Mouse

SwissProt: Q9WV63 Rat

Unigene: 558351 Human

Unigene: 355686 Mouse

Unigene: 17829 Rat

Unigene: 218992 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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