| 產(chǎn)品編號(hào) | bs-16992R-AP |
| 英文名稱 | Rabbit Anti-KIAA1161/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的KIAA1161蛋白抗體 |
| 別 名 | K1161_HUMAN; KIAA1161; Uncharacterized family 31 glucosidase KIAA1161. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 新陳代謝 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 81kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1161 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: KIAA1161 is a 714 amino acid protein that belongs to the glycosyl hydrolase 31 family and functions as a putative glucosidase. This single-pass type II membrane protein is post-translationally phosphorylated at serine 44 and glycosylated at amino acid positions 240 and 250. The gene encoding KIAA1161 maps to human chromosome 9, which consists of about 145 million bases, comprises approximately 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Function: Putative glucosidase. Subcellular Location: Membrane. Similarity: Belongs to the glycosyl hydrolase 31 family. Database links: Entrez Gene: 57462 Human Entrez Gene: 329828 Mouse SwissProt: Q6NSJ0 Human SwissProt: Q69ZQ1 Mouse Unigene: 522083 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
