| 產(chǎn)品編號(hào) | bs-16757R-BF488 |
| 英文名稱 | Rabbit Anti-KLHDC10/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的KLHDC10蛋白抗體 |
| 別 名 | Kelch domain containing 10; Kelch domain-containing protein 10; KIAA0265; KLD10_HUMAN; Klhdc10; OTTHUMP00000212347; PNAS 119; Scruin like at the midline homolog; Slim. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLHDC10 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: KLHDC10 is a 442 amino acid protein that contains six kelch repeats. Expressed in fetal brain, liver, lung, kidney and placenta, KLHDC10 exists as two alternatively spliced isoforms. The gene encoding KLHDC10 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia. Subunit: Interacts with CUL2, TCEB1 and TCEB2; may be the substrate recognition component of an E3 ubiquitin ligase complex. Subcellular Location: Nucleus Similarity: Contains 6 Kelch repeats. Database links: Entrez Gene: 23008 Human Entrez Gene: 76788 Mouse SwissProt: Q6PID8 Human SwissProt: Q6PAR0 Mouse Unigene: 520710 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
