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Rabbit Anti-DMRTA2/Gold Conjugated antibody (bs-14348R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14348R-Gold
英文名稱 Rabbit Anti-DMRTA2/Gold Conjugated antibody
中文名稱 膠體金標記的DMRTA2蛋白抗體
別    名 DMRT A2; DMRT like family A2; DMRT5; DMRTA 2; dmrta2; DMTA2_HUMAN; Doublesex- and mab-3-related transcription factor 5; Doublesex- and mab-3-related transcription factor A2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DMRTA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
May be involved in sexual development.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the DMRT family.
Contains 1 DM DNA-binding domain.

Database links:

Entrez Gene: 63950 Human

Entrez Gene: 242620 Mouse

Entrez Gene: 313471 Rat

SwissProt: Q5TFQ3 Human

SwissProt: Q96SC8 Human

SwissProt: A2A9A2 Mouse

Unigene: 334481 Human

Unigene: 32825 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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