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Rabbit Anti-Nkx2.6/Gold Conjugated antibody (bs-19275R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19275R-Gold
英文名稱 Rabbit Anti-Nkx2.6/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的轉(zhuǎn)錄因子同源蛋白Nkx2.6抗體
別    名 CSX2; Homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; Homeobox protein Nkx-2.6; Homeobox protein Nkx2.6; NK2 homeobox 6; NK2 transcription factor related, locus 6 (Drosophila); NKX2-6; NKX26_HUMAN; NKX2F; NKX4 2; Tinman paralog.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 心血管  細(xì)胞生物  發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nkx2.6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011]

Function:
In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.

Subcellular Location:
Nucleus

DISEASE:
[MIM:217095]: A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle.

Similarity:
Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 137814 Human

Entrez Gene: 18092 Mouse

Omim: 611770 Human

SwissProt: A6NCS4 Human

SwissProt: P43688 Mouse

Unigene: 532654 Human




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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