產(chǎn)品編號 | bs-15404R-Cy7 |
英文名稱 | Rabbit Anti-HAGH/Cy7 Conjugated antibody |
中文名稱 | Cy7標記的羥酰谷胱甘肽水解酶蛋白抗體 |
別 名 | GLO2; GLX II; Glyoxalase II; HAGH; HAGH1; Hydroxyacyl glutathione hydrolase; Hydroxyacylglutathione hydrolase, mitochondrial; GLO2_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細胞生物 免疫學 神經(jīng)生物學 新陳代謝 線粒體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 32kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HAGH |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP). Glyoxalase I and Gyloxalase II (also designated hydroxyacyl glutathione hydrolase or HAGH) are members of the Gyloxalase family. The Gyloxalase II enzyme is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form reduced glutathione and D-lactic acid. It exists only as a monomer and binds two zinc ions per subunit. Glyoxalase II contains 260 amino acids. It is detected in the mitochondria and cytosol of mammals. Both Glyoxalase I and Gyloxalase II are detected at a higher activity level in breast cancer tissues than with matched unaffected tissues. This suggests that glyoxalase inhibitor drugs may be effective in the treatment of cancer. Function: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. Subunit: Monomer. Subcellular Location: Isoform 1: Mitochondrion matrix. Isoform 2: Cytoplasm. Tissue Specificity: Expressed in liver and kidney. Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. Database links: Entrez Gene: 3029 Human Entrez Gene: 14651 Mouse Omim: 138760 Human SwissProt: Q16775 Human SwissProt: Q99KB8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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