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Rabbit Anti-COX6B2/APC Conjugated antibody (bs-14009R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14009R-APC
英文名稱 Rabbit Anti-COX6B2/APC Conjugated antibody
中文名稱 APC標記的細胞色素C氧化酶蛋白6B2抗體
別    名 Cancer/testis antigen 59; COX VIb-2; Cox6b2; COXVIb-2; COXVIb2; CT59; CX6B2_HUMAN; Cytochrome c oxidase subunit 6B2; Cytochrome c oxidase subunit VIb; Cytochrome c oxidase subunit VIb isoform 2; cytochrome c oxidase subunit VIb polypeptide 2 (testis); Cytochrome c oxidase subunit VIb testes specific; Cytochrome c oxidase subunit VIb, testis-specific isoform; FLJ46422; MGC119094; testis-specific isoform.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞類型標志物  新陳代謝  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COX6B2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.

Function:
Connects the two COX monomers into the physiological dimeric form.

Subcellular Location:
Mitochondrion intermembrane space.

Tissue Specificity:
Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.

Similarity:
Belongs to the cytochrome c oxidase subunit 6B family.

Database links:

Entrez Gene: 125965 Human

Entrez Gene: 333182 Mouse

Entrez Gene: 654441 Rat

SwissProt: Q6YFQ2 Human

SwissProt: Q80ZN9 Mouse

SwissProt: Q6YFQ1 Rat

Unigene: 550544 Human

Unigene: 29625 Mouse

Unigene: 97699 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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