產(chǎn)品編號(hào) | bs-13940R-AP |
英文名稱 | Rabbit Anti-CHST9/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的碳水化合物磺基轉(zhuǎn)移酶8抗體 |
別 名 | Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 8; Carbohydrate sulfotransferase 8; CHST 8; GalNAc 4 O sulfotransferase 1; GalNAc 4 ST1; CHST9_HUMAN; GalNAc4ST 1; GalNAc4ST; GALNAC4ST1; N acetylgalactosamine 4 O sulfotransferase 1; N acetylgalactosamine 4 O sulfotransferase. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 52kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CHST9 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011] Function: Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin. Subcellular Location: Secreted and Golgi apparatus membrane. Tissue Specificity: Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord. Similarity: Belongs to the sulfotransferase 2 family. Database links: Entrez Gene: 83539 Human Entrez Gene: 71367 Mouse Omim: 610191 Human SwissProt: Q7L1S5 Human SwissProt: Q76EC5 Mouse Unigene: 44584 Human Unigene: 706552 Human Unigene: 329304 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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