| 產(chǎn)品編號 | bs-11763R-BF647 |
| 英文名稱 | Rabbit Anti-SULT4A1/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的腦磺基轉(zhuǎn)移酶樣蛋白4A1抗體 |
| 別 名 | BR STL 1; Brain sulfotransferase like protein; Brain sulphotransferase like; BRSTL1; hBR STL 1; hBR STL; Nervous system cytosolic sulfotransferase; Nervous system sulfotransferase; NST; Sulfotransferase 4A1; Sulfotransferase family 4A member 1; Sulfotransferase related protein; SULTX3; ST4A1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SULT4A1 (221-284aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Sulfation is an essential conjugation reaction that increases the water solubility of many compounds, thereby influencing their renal excretion and also resulting in the formation of active metabolites. SULT4A1 (sulfotransferase family 4A, member 1), whose alternative names include brain sulfotransferase-like protein, nervous system sulfotransferase, NST, SULTX3, hBR-STL-1, BRSTL1, BR-STL-1, MGC40032 and DJ388M5.3, is a 284 amino acid protein showing cytoplasmic localization. As a member of the sulfotransferase 1 family, SULT4A1 plays a role in elimination of xenobiotics, activation of procarcinogens and regulation of hormones. SULT4A1 is highly expressed in cerebral cortex and frontal lobe, with lower expression in cerebellum, temporal and occipital lobes. Two SULT4A1 isoforms exist to alternative splicing events. The gene encoding SULT4A1 maps to human chromosome 22q13.2, a region which has been implicated in predisposition to schizophrenia. Function: SULT4A1 is a member of the sulfotransferase family. It is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. It may catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. There are two named isoforms. Subcellular Location: Cytoplasmic Tissue Specificity: Highly expressed in the cerebral cortex andfrontal lobe, slightly less in the cerebellum, occipital andtemporal lobes, relatively low in the medulla and putamen, andlowest in the spinal cord. No expression detected in the pancreas(PubMed:10698717). Highly expressed in fetal brain and occipitallobe, slightly less in the whole brain, frontal lobe, hippocampus,and lung, very low expression in cerebellum, medulla oblongata,temporal lobe, testis, kidney and appendix (PubMed:12039030). Similarity: Belongs to the sulfotransferase 1 family. Database links: Entrez Gene: 25830 Human Entrez Gene: 29859 Mouse Entrez Gene: 100009444 Rabbit Omim: 608359 Human SwissProt: Q9BR01 Human SwissProt: P63046 Mouse Unigene: 189810 Human Unigene: 248796 Mouse Unigene: 162965 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
