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Rabbit Anti-NRSN1/Gold Conjugated antibody (bs-11915R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11915R-Gold
英文名稱 Rabbit Anti-NRSN1/Gold Conjugated antibody
中文名稱 膠體金標記的神經(jīng)囊泡膜蛋白1抗體
別    名 Neurensin-1; Neuro-p24; NRSN1; NRSN1_HUMAN; p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24; VMP.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  發(fā)育生物學  神經(jīng)生物學  信號轉(zhuǎn)導  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRSN1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.

Function:
May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.

Subcellular Location:
Membrane. Localizes mainly to neurites.

Tissue Specificity:
Expressed in brain. Not detectable in other tissues tested.

Similarity:
Belongs to the VMP family.

Database links:

Entrez Gene: 140767 Human

Entrez Gene: 22360 Mouse

Entrez Gene: 291129 Rat

SwissProt: Q8IZ57 Human

SwissProt: P97799 Mouse

Unigene: 726270 Human

Unigene: 4766 Mouse

Unigene: 225156 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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