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Rabbit Anti-NT-3/BF488 Conjugated antibody (bs-4724R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4724R-BF488
英文名稱 Rabbit Anti-NT-3/BF488 Conjugated antibody
中文名稱 BF488標記的神經(jīng)營養(yǎng)因子3抗體
別    名 HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; Neurotrophin 3 precursor; Neurotrophin-3; Neurotrophin3; NGF 2; NGF-2; NGF2; NT 3; NT-3; NT3; NTF 3; NTF3; NTF3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14/28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NT-3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008].

Function:
Seems to promote the survival of visceral and proprioceptive sensory neurons.

Subcellular Location:
Secreted.

Tissue Specificity:
Brain and peripheral tissues.

Similarity:
Belongs to the NGF-beta family.

Database links:

Entrez Gene: 4908 Human

Entrez Gene: 18205 Mouse

Entrez Gene: 81737 Rat

Omim: 162660 Human

SwissProt: P20783 Human

SwissProt: P20181 Mouse

SwissProt: P18280 Rat

Unigene: 99171 Human

Unigene: 267570 Mouse

Unigene: 9715 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

一種內(nèi)源型神經(jīng)遞質(zhì),分子量為28kDa的堿性多肽,屬神經(jīng)營養(yǎng)蛋白家族。與NGF和BDNF具有序列同源性,為培養(yǎng)的神經(jīng)嵴細胞的促細胞分裂劑。此抗體與NGF、BDNF無交叉反應(yīng)。
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