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Rabbit Anti-VDAC3/APC Conjugated antibody (bs-7647R-APC)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7647R-APC
英文名稱 Rabbit Anti-VDAC3/APC Conjugated antibody
中文名稱 APC標(biāo)記的線粒體外膜孔蛋白3/電壓依賴陰離子通道蛋白3抗體
別    名 hVDAC3; mVDAC3; Outer mitochondrial membrane protein porin 3; voltage dependent anion channel 3; VDAC3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, DogZebrafish,Orangutan)
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VDAC3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).

Subcellular Location:
Mitochondrion outer membrane.

Tissue Specificity:
Widely expressed. Highest in testis.

Similarity:
Belongs to the eukaryotic mitochondrial porin family.

Database links:

Entrez Gene: 426793 Chicken

Entrez Gene: 282716 Cow

Entrez Gene: 7419 Human

Entrez Gene: 22335 Mouse

Entrez Gene: 83532 Rat

Omim: 610029 Human

SwissProt: Q9MZ13 Cow

SwissProt: Q9Y277 Human

SwissProt: Q60931 Mouse

SwissProt: Q9TT13 Rabbit

SwissProt: Q9R1Z0 Rat

Unigene: 699301 Human

Unigene: 227704 Mouse

Unigene: 107287 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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