產品編號 | bs-7080R-AP |
英文名稱 | Rabbit Anti-Nucleolar protein 3/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標記的核仁蛋白3抗體 |
別 名 | Apoptosis repressor with CARD; ARC; Muscle enriched cytoplasmic protein; MYC; Myp; NOP; Nop30; Nucleolar protein 3 (apoptosis repressor with CARD domain); Nucleolar protein 3; Nucleolar protein of 30 kDa; NOL3_MOUSE . |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 細胞生物 染色質和核信號 細胞凋亡 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Mouse, (predicted: Human, Rat, Dog, Cow, Rabbit, ) |
產品應用 | IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse Nucleolar protein 3/Apoptosis repressor with CARD |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis. Function: May be involved in RNA splicing (By similarity). Subunit: Interacts with SFRS9/SRp30c, NPM1, CASP2, CASP8 and TFPT (By similarity). Subcellular Location: Cytoplasm and Nucleus > nucleolus. Similarity: Contains 1 CARD domain. Database links: Entrez Gene: 8996 Human Entrez Gene: 78688 Mouse Omim: 605235 Human SwissProt: O60936 Human SwissProt: Q9D1X0 Mouse Unigene: 513667 Human Unigene: 204876 Mouse Unigene: 475715 Mouse Unigene: 86956 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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