| 產(chǎn)品編號(hào) | bs-7566R-BF350 |
| 英文名稱(chēng) | Rabbit Anti-RHBDD3/BF350 Conjugated antibody |
| 中文名稱(chēng) | BF350標(biāo)記的垂體瘤細(xì)胞凋亡抗體 |
| 別 名 | C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RHBDD3 (101-200aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Contains 1 UBA domain Database links: Entrez Gene: 25807 Human Entrez Gene: 279766 Mouse SwissProt: Q9Y3P4 Human SwissProt: Q8BP97 Mouse Unigene: 106730 Human Unigene: 260866 Mouse Unigene: 9606 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. RHBDD3分子是一個(gè)全新的TLR信號(hào)途徑的負(fù)向調(diào)控蛋白分子,是一個(gè)能夠顯著抑制自身免疫性疾病發(fā)生的效應(yīng)分子,RHBDD3控制機(jī)體避免發(fā)生過(guò)度的免疫應(yīng)答、防止自身免疫性疾病的發(fā)生具有重要意義。 |
