| 產(chǎn)品編號(hào) | bs-0791R-APC |
| 英文名稱 | Rabbit Anti-CGRP/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的降鈣素基因相關(guān)肽2抗體 |
| 別 名 | CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide beta; CGRP; CGRP II; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648; CALCA_HUMAN; CALCB_HUMAN; Calcitonin gene-related peptide 2; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II; CGRP-II; CGRP-I. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Chicken, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 3.8kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CGRP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009] Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. Subcellular Location: Secreted. Similarity: Belongs to the calcitonin family. Database links: Entrez Gene: 796 Human Entrez Gene: 797 Human Entrez Gene: 116903 Mouse Entrez Gene: 12310 Mouse Omim: 114130 Human Omim: 114160 Human SwissProt: P01258 Human SwissProt: P06881 Human SwissProt: P10092 Human SwissProt: P70160 Mouse SwissProt: Q99JA0 Mouse Unigene: 37058 Human Unigene: 534305 Human Unigene: 273838 Mouse Unigene: 4361 Mouse Unigene: 88080 Rat Unigene: 90085 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CGRP活性多肽，有37個(gè)氨基酸組成，具有多種生理功能，其藥理作用已受到廣泛重視. CGRP （又稱CGRP-1/2或CGRPa/β）廣泛分布于神經(jīng)系統(tǒng)的一種神經(jīng)肽，在外周及脊髓參與傷害性信息的傳遞及痛敏化的形成，并與P物質(zhì)、興奮性氨基酸、辣椒素1型受體、趨化因子、激活素、大麻素受體、阿片受體、神經(jīng)生長因子、血管活性腸肽、5-羥色胺、糖皮質(zhì)激素等生物活性物質(zhì)或受體在痛覺調(diào)制過程中存在相互影響。 |
