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Rabbit Anti-LILRB1/Cy5.5 Conjugated antibody (bs-2634R-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2634R-Cy5.5
英文名稱 Rabbit Anti-LILRB1/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的細胞表面免疫球蛋白樣轉錄因子2抗體
別    名 LILRB1; Leukocyte immunoglobulin-like receptor subfamily B member 1; Leukocyte immunoglobulin-like receptor 1; LIR-1; Immunoglobulin-like transcript 2; Monocyte/macrophage immunoglobulin-like receptor 7; ILT-2; MIR-7; CD85 antigen-like family member J; CD85j; ILT2; LIR1; MIR7; CD85; CD85 antigen; CD85j antigen; Ig like transcript 2; leukocyte Ig like receptor 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產(chǎn)品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ILT2 (151-190aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Subunit:
Binds PTPN6 when phosphorylated. Binds FCGR1A.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.

Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 10859 Human

Omim: 604811 Human

SwissProt: Q8NHL6 Human

Unigene: 667388 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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