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Rabbit Anti-TNFSF18/Gold Conjugated antibody (bs-2456R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-2456R-Gold
英文名稱 Rabbit Anti-TNFSF18/Gold Conjugated antibody
中文名稱 膠體金標記的腫瘤壞死因子配體超家族成員18抗體
別    名 Tumor necrosis factor ligand superfamily member 18; AITRL; GITRL; hGITRL; TL6; Activation inducible TNF related ligand; AITR ligand ; AITRL; GITR ligand; ; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; MGC138237; Tumor necrosis factor (ligand) superfamily member 18; GITR Ligand; TNF18_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  細胞凋亡  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF18
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq].

Function:
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

Subunit:
Homodimer. Homotrimer.

Subcellular Location:
Cell membrane; Single-pass type II membrane protein.

Tissue Specificity:
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 8995 Human

Entrez Gene: 240873 Mouse

Omim: 603898 Human

SwissProt: Q9UNG2 Human

SwissProt: Q7TS55 Mouse

Unigene: 248197 Human

Unigene: 276823 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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