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Rabbit Anti-eEF1A1/PE Conjugated antibody (bs-2503R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2503R-PE
英文名稱 Rabbit Anti-eEF1A1/PE Conjugated antibody
中文名稱 PE標(biāo)記的翻譯延伸因子EF-1a抗體
別    名 Elongation Factor 1, Alpha; EF1 Alpha; eukaryotic translation elongation factor 1 alpha 1; CCS3; eEF1A-1; EF-Tu; EF1A; Elongation factor Tu; GRAF-1EF; PTI1; elongation factor 1-alpha 1; EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; MGC125172; SI; Eef1a1; EF1A1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EF1 alpha
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
eEF1A1 is an isoform of the alpha subunit of the elongation factor 1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. It promotes the GTP dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome (referenced from entrez gene and swissprot).

Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle

Post-translational modifications:
ISGylated.

Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Database links:

Entrez Gene: 1915 Human

Entrez Gene: 13627 Mouse

Entrez Gene: 171361 Rat

Omim: 130590 Human

SwissProt: P68104 Human

SwissProt: P10126 Mouse

SwissProt: P62630 Rat

Unigene: 520703 Human

Unigene: 535192 Human

Unigene: 586423 Human

Unigene: 695681 Human

Unigene: 713109 Human

Unigene: 138471 Mouse

Unigene: 335315 Mouse

Unigene: 360075 Mouse

Unigene: 391071 Mouse

Unigene: 468942 Mouse

Unigene: 144660 Rat

Unigene: 965 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肽鏈延長(zhǎng)因子1A-1(peptide elongation factor 1A-1,eEF1A-1)是真核細(xì)胞蛋白翻譯過程中肽鏈延長(zhǎng)復(fù)合物的重要構(gòu)成成分,具有調(diào)節(jié)蛋白合成及促發(fā)凋亡等多種作用.
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