91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關于我們  聯(lián)系我們
精品人妻无码一区二区三区淑枝,亚洲精品成a人在线观看,国产丨熟女丨国产熟女视频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-SNIP1/APC Conjugated antibody (bs-11260R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11260R-APC
英文名稱 Rabbit Anti-SNIP1/APC Conjugated antibody
中文名稱 APC標記的Smad核相互作用蛋白1抗體
別    名 FHA domain-containing protein SNIP1; FLJ12553; Smad nuclear interacting protein (Smad nuclear interacting); Smad nuclear interacting protein; Smad nuclear-interacting protein 1; SNIP1 (Smad nuclear interacting protein); SNIP1; SNIP1_HUMAN; Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75).  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉(zhuǎn)導  生長因子和激素  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNIP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.

Function:
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis.

Subunit:
Binds SMAD4 and CREBBP/EP300. Binds the SMAD1/OAZ1/PSMB4 complex. Interacts with DROSHA and SMARCA4. Component of the SNARP complex which consists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN.

Subcellular Location:
Nucleus.

Tissue Specificity:
Tissue specificityUbiquitous, with highest expression in heart and skeletal muscle.

Post-translational modifications:
Degraded by the proteasome upon binding to the SMAD1/OAZ1/PSMB4 complex.

DISEASE:
Defects in SNIP1 are the cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED) [MIM:614501]. A disease characterized by severe psychomotor retardation, intractable seizures, dysmorphic features, and a lumpy skull surface. Patients are hypotonic and have poor feeding in the neonatal period.

Similarity:
Contains 1 FHA domain.

Database links:
UniProtKB/Swiss-Prot: Q8TAD8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.rvdoil.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久这里面都是老女人拍拍拍 | A级成人婬片免费看 | 依依妖妖美女操逼视频 | 成人爱爱免费视频 | 亚洲无码在线播放 | 99久久无码一区人妻A片红豆 | 久久精品99国产国产精 | 国产寡妇婬乱A毛片视频杏吧传媒 | 欧美成人一区三区无码乱码A片 | 国产剧情亚洲无码视频 | 四川一级特黄A片免费 | 中文字幕無碼亂倫系列 | 欧一美一色一伦一区二区三区 | 国产精品99久久久久久www | 五月天韩国亚洲三小时导航 | 人妻熟女视频影音先锋 | 精品人妻无码一区二区三区淑枝 | 久久精品国产一区二区电影 | 成人h精品动漫一区二区三区 | 国产精品一品在线免费观看 | 女人做爰高潮A片免费 | 亚洲一区二区三区在线观看视频 | 91午夜伦伦电影理论片 | 缅甸午夜性猛交XXXX | 日韩欧美一区二区三区久久婷婷 | 91小仙女jK白丝袜呻吟 | 少妇黃色A片三級三級三級 精品秘 无码一区二区久久 | 国产一级网站在线观看 | 99久久久久久久无码 | 色窝窝51精品国产人妻消防 | 97人人爽人人爽人人爽 | 99人妻碰碰碰久久久久禁片 | 嫩模BBw搡BBBB搡BBBB | 精品在线免费视频 | 影音先锋在线资源播放 | 欧性猛交ⅩXXX乱大交 | 中文字幕 无码 一区 二区 国产 | 人妻熟女中出在线4k | 91女神娇喘呻吟高潮喷水 | 色欲狠狠躁天天躁无码中文字幕 | 日本熟妇乱妇熟色A片蜜桃 欧美成人精品A片人妻83 |