| 產(chǎn)品編號(hào) | bs-6626R-Gold |
| 英文名稱 | Rabbit Anti-GPR24/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的G蛋白偶聯(lián)受體24抗體 |
| 別 名 | MCHR; G protein coupled receptor 24; GPCR MCH1; GPCR SLC/MCH1; GPR24; MCH receptor 1; MCH1R; Melanin concentrating hormone receptor 1; SLC-1; Somatostatin receptor like protein; MCHR1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Dog, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MCHR/GPR24 (81-125aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: MCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin. Function: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Subunit: Interacts with NCDN. Subcellular Location: Cell Membrane; multi-pass membrane protein Tissue Specificity: Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 2847 Human Entrez Gene: 207911 Mouse Omim: 601751 Human SwissProt: Q99705 Human SwissProt: Q8JZL2 Mouse Unigene: 248122 Human Unigene: 323523 Mouse Unigene: 10822 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
