產(chǎn)品編號 | bs-1389R-Gold |
英文名稱 | Rabbit Anti-Cyclin G/Gold Conjugated antibody |
中文名稱 | 膠體金標記的周期素G抗體 |
別 名 | CCNG 1; CCNG; CCNG1; CYCG1; Cyclin G; CCNG1_HUMAN; Cyclin-G; Cyclin G1; CyclinG1; Cyclin-G1. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領域 | 細胞生物 染色質(zhì)和核信號 細胞周期蛋白 表觀遺傳學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 34kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Cyclin G |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive. Function: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity). Subcellular Location: Nucleus. DNA replication foci after DNA damage. Tissue Specificity: High levels in skeletal muscle, ovary, kidney and colon. Similarity: Belongs to the cyclin family. Cyclin G subfamily. Database links: Entrez Gene: 900 Human Omim: 601578 Human SwissProt: P51959 Human Unigene: 79101 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Cyclin G的生物功能還沒有完全清楚,他是細胞周期蛋白家族中近來發(fā)現(xiàn)的新成員,也是已知的唯一受到腫瘤抑制基因p53調(diào)控的細胞周期蛋白。 近年來經(jīng)研究發(fā)現(xiàn),Cyclin G可能有促進細胞增長的作用,在細胞增殖和神經(jīng)再生中的可能起到一定的作用。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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