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Rabbit Anti-DAP5/PE-Cy3 Conjugated antibody (bs-1350R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1350R-PE-Cy3
英文名稱 Rabbit Anti-DAP5/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的死亡相關(guān)蛋白5抗體
別    名 DAP-5; DAP 5; Death Associated Protein-5; Death associated protein 5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; Nat1; Novel APOBEC-1 target 1; Translation repressor NAT1; IF4G2_HUMAN; p97.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號(hào)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 102kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DAP-5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Database links:

Entrez Gene: 1982 Human

Entrez Gene: 13690 Mouse

Entrez Gene: 361628 Rat

Omim: 602325 Human

SwissProt: P78344 Human

SwissProt: Q62448 Mouse

Unigene: 183684 Human

Unigene: 185453 Mouse

Unigene: 103276 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

DAP-5又稱p97, 是白細(xì)胞轉(zhuǎn)移抑制因子4G (ELF4G)家族成員. DAP-5在各種種系表達(dá)廣泛并高度保守。
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