產(chǎn)品編號(hào) | bsm-30240A-PE |
英文名稱 | mouse CD18/PE |
中文名稱 | PE標(biāo)記小鼠CD18單克隆抗體 |
別 名 | Integrin beta 2; 95 subunit beta; CD 18; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150; Complement receptor C3 beta subunit; Complement receptor C3 subunit beta; Integrin beta chain beta 2; Integrin beta-2; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITB2_MOUSE; ITGB2; LAD; LCAMB; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C; Leukocyte cell adhesion molecule CD18; LFA 1; LFA1; Lymphocyte function associated antigen 1; MAC 1; MAC1; MF17; MFI7; |
抗體來源 | Rat |
克隆類型 | Monoclonal |
克 隆 號(hào) | 2D1 |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 82kDa |
檢測分子量 | 90-95 |
性 狀 | Liquid |
亞 型 | Rat IgG2a, k |
純化方法 | Affinity purified by Protein G |
緩 沖 液 | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
保存條件 | Store at 2-8℃. Protect from light. Avoid freezing. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Enables amyloid-beta binding activity and complement component C3b binding activity. Contributes to cargo receptor activity. Involved in several processes, including cellular response to low-density lipoprotein particle stimulus; endocytosis; and positive regulation of leukocyte adhesion to vascular endothelial cell. Acts upstream of or within several processes, including activated T cell proliferation; integrin-mediated signaling pathway; and leukocyte migration. Located in external side of plasma membrane and membrane raft. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including alimentary system; genitourinary system; heart and pericardium; hemolymphoid system; and nervous system. Used to study leukocyte adhesion deficiency 1 and psoriasis. Human ortholog(s) of this gene implicated in coronary restenosis; leukocyte adhesion deficiency; and leukocyte adhesion deficiency 1. Orthologous to human ITGB2 (integrin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022] SWISS: P11835 Gene ID: 16414 |
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