| 產(chǎn)品編號 | bs-12740R |
| 英文名稱 | PMM1 Rabbit pAb |
| 中文名稱 | 磷酸甘露糖變位酶1抗體 |
| 別 名 | Brain glucose-1, 6-bisphosphatase; phosphomannomutase 1; PMM 1; pmm1; PMM1_HUMAN; PMMH 22; PMMH-22; PMMH22; Sec53. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 30 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PMM1: 31-130/262 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008] Function: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Subcellular Location: Cytoplasm. Tissue Specificity: Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle. Similarity: Belongs to the eukaryotic PMM family. SWISS: Q92871 Gene ID: 5372 Database links: Entrez Gene: 5372 Human Entrez Gene: 29858 Mouse Omim: 601786 Human SwissProt: Q92871 Human SwissProt: O35621 Mouse Unigene: 75835 Human Unigene: 18939 Mouse |
| 產(chǎn)品圖片 |
Sample: 293T(Human) Cell Lysate at 40 ug
Primary: Anti-PMMI (bs-12740R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30 kD
Observed band size: 30 kD
Sample: Panc-1(Human) Cell Lysate at 40 ug
Primary: Anti-PMMI (bs-12740R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30 kD
Observed band size: 30 kD
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