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RABL2A Rabbit pAb (bs-19722R)  
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產(chǎn)品編號(hào) bs-19722R
英文名稱 RABL2A Rabbit pAb
中文名稱 RABL2A蛋白抗體
別    名 FLJ78724; MGC117180; OTTHUMP00000045491; OTTHUMP00000045492; OTTHUMP00000045493; OTTHUMP00000203788; OTTHUMP00000203792; Rab-like protein 2A; RABL2A; RBL2A_HUMAN; RP11-395L14.2.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 26 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse RABL2A: 161-228/228 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Two alternatively spliced transcript variants have been identified, both encoding the same protein. [provided by RefSeq, Jul 2008]

Function:
Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail (By similarity).

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
E9Q9D5

Gene ID:
68708

Database links:

Entrez Gene: 11159 Human

Entrez Gene: 362987 Rat

Omim: 605412 Human

SwissProt: Q9UBK7 Human

Unigene: 446425 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RABL2A) Polyclonal Antibody, Unconjugated (bs-19722R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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