| 產(chǎn)品編號 | bs-18985R |
| 英文名稱 | N4BP2 Rabbit pAb |
| 中文名稱 | E3泛素連接酶NEDD4結(jié)合蛋白2抗體 |
| 別 名 | B3BP; BCL 3 binding protein; BCL3 binding protein; FLJ10680; KIAA1413; Nedd4 binding protein 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 199 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human N4BP2: 281-380/1770 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq, Jul 2008] Function: Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination. Subunit: Binds NEDD4 By similarity. Binds BCL3 and CREBBP. Subcellular Location: Cytoplasm Post-translational modifications: Ubiquitinated; this targets the protein for degradation by the proteasome Similarity: Contains 1 CUE domain. Contains 1 Smr domain. SWISS: Q86UW6 Gene ID: 55728 Database links: Entrez Gene: 55728 Human SwissProt: Q86UW6 Human Unigene: 396494 Human |
