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MLIP/C6orf142 Rabbit pAb (bs-18952R)  
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產(chǎn)品編號(hào) bs-18952R
英文名稱 MLIP/C6orf142 Rabbit pAb
中文名稱 6號(hào)染色體開放閱讀框142抗體
別    名 C6orf142; MLIP; MLIP_HUMAN; Muscle enriched A type lamin interacting protein; Muscular LMNA-interacting protein; Muscular-enriched A-type laminin-interacting protein; RP11-642N5.1.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MLIP/C6orf142: 301-400/458 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf142 gene product has been provisionally designated C6orf142 pending further characterization.

Subcellular Location:
Nucleus. Nucleus envelope. Nucleus > PML body.

Tissue Specificity:
Primarily expressed in heart and skeletal muscle. Also detected in liver.

SWISS:
Q5VWP3

Gene ID:
90523

Database links:

Entrez Gene: 90523 Human

Omim: 614106 Human

SwissProt: Q5VWP3 Human

Unigene: 449276 Human



產(chǎn)品圖片
Sample: H9C2(Rat) Cell Lysate at 30 ug Primary: Anti-MLIP (bs-18952R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 53 kD
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-MLIP (bs-18952R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 53 kD
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