產(chǎn)品編號(hào) | bs-18482R |
英文名稱 | ZDHHC23 Rabbit pAb |
中文名稱 | ZDHHC23蛋白抗體 |
別 名 | DHHC-23; DHHC-containing protein 11; Gm1751; Gm779; nidd; Probable palmitoyltransferase ZDHHC23; ZDH23_HUMAN; Zdhhc23; Zinc finger DHHC domain-containing protein 23. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 46 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZDHHC23: 1-100/409 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ZDHHC23 is a 409 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. ZDHHC23 may play a role in NOS1 regulation and targets the synaptic membrane. By regulating the enzymatic activity of NOS1, ZDHHC23 may effect different pathological conditions including nerve regeneration, neuron loss or survival and pain processing. Function: May be involved in NOS1 regulation and targeting to the synaptic membrane. Subcellular Location: Membrane. Similarity: Belongs to the DHHC palmitoyltransferase family. Contains 1 DHHC-type zinc finger. SWISS: Q8IYP9 Gene ID: 254887 Database links: Entrez Gene: 254887 Human Entrez Gene: 332175 Mouse SwissProt: Q8IYP9 Human SwissProt: Q5Y5T3 Mouse Unigene: 21902 Human Unigene: 327852 Mouse Unigene: 43304 Rat |
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