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LHFPL5 Rabbit pAb (bs-18242R)  
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產(chǎn)品編號 bs-18242R
英文名稱 LHFPL5 Rabbit pAb
中文名稱 脂肪瘤高遷移率融合蛋白樣蛋白5抗體
別    名 Lhfpl5; LHPL5_HUMAN; Lipoma HMGIC fusion partner like 5; Lipoma HMGIC fusion partner-like 5 protein.  
研究領域 細胞生物  免疫學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Rat (predicted: Mouse,Sheep,Cow,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LHFPL5: 1-100/219 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis. [provided by RefSeq, Jul 2008]

Function:
May function in hair bundle morphogenesis.

Subcellular Location:
Membrane.

DISEASE:
Defects in LHFPL5 are a cause of deafness autosomal recessive type 67 (DFNB67) [MIM:610265]. DFNB67 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Similarity:
Belongs to the LHFP family.

SWISS:
Q8TAF8

Gene ID:
222662

Database links:

Entrez Gene: 222662 Human

Entrez Gene: 328789 Mouse

Entrez Gene: 294303 Rat

Omim: 609427 Human

SwissProt: Q8TAF8 Human

SwissProt: Q4KL25 Mouse

SwissProt: Q5PPI7 Rat

Unigene: 367947 Human

Unigene: 284760 Mouse

Unigene: 161732 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LHFPL5) Polyclonal Antibody, Unconjugated (bs-18242R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Human Brain Glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LHFPL5) Polyclonal Antibody, Unconjugated (bs-18242R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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