產(chǎn)品編號(hào) | bs-16988R |
英文名稱 | KIAA1045 Rabbit pAb |
中文名稱 | KIAA1045蛋白抗體 |
別 名 | K1045_HUMAN; Kiaa1045; Protein KIAA1045; RP11-392A14.4. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 鋅指蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 45 kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1045: 51-150/400 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
KIAA1045 is a 400 amino acid protein that contains one PHD-type zinc finger. The gene encoding KIAA1045 maps to human chromosome 9p13.3. Chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome. Considered to play a role in gender determination, deletion of the distal portion of chromosome 9p can lead to development of male to female sex reversal, the phenotype of a female with a male XY genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of a BCR-ABL fusion protein often found in leukemias. Similarity: Contains 1 PHD-type zinc finger. SWISS: Q9UPV7 Gene ID: 23349 Database links: Entrez Gene: 23349 Human Entrez Gene: 230085 Mouse SwissProt: Q9UPV7 Human SwissProt: Q80TL4 Mouse Unigene: 7989 Human |
產(chǎn)品圖片 | |
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