產(chǎn)品編號 | bs-16319R |
英文名稱 | GRK7 Rabbit pAb |
中文名稱 | G蛋白偶聯(lián)受體激酶7抗體 |
別 名 | G protein coupled receptor kinase 7; G protein coupled receptor kinase GRK7; G protein-coupled receptor kinase 7; G protein-coupled receptor kinase GRK7; GPRK 7; GPRK7; GRK 7; GRK7; GRK7_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 激酶和磷酸酶 G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 62 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GRK7: 351-450/553 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008] Function: Phosphorylates cone opsins thereby initiating their deactivation. Subcellular Location: Membrane. Tissue Specificity: Retina. Cones and rod. Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. Contains 1 RGS domain. SWISS: Q8WTQ7 Gene ID: 131890 Database links: Entrez Gene: 131890 Human Omim: 606987 Human SwissProt: Q8WTQ7 Human Unigene: 680654 Human |
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