| 產(chǎn)品編號 | bs-14342R |
| 英文名稱 | DLK2 Rabbit pAb |
| 中文名稱 | 穿膜蛋白DLK2抗體 |
| 別 名 | AI413481; delta like 2 homolog; delta like protein 2; delta-like 2 homolog(Drosophila); DLK 2; DLK-2; Dlk2; DLK2_HUMAN; EGF like domain containing protein 9; EGF like domain multiple 9; EGF-like protein 9; EGFL 9; EGFL9; Epidermal growth factor-like protein 9; MGC111055; MGC2487; Multiple EGF like domain protein 9; OTTHUMP00000016449; OTTHUMP00000016451; Protein delta homolog 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 生長因子和激素 結(jié)合蛋白 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DLK2: 241-340/383 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DLK2 is a 383 amino acid single-pass transmembrane protein with six tandem EGF-like repeats in the putative extracellular domain, which is characteristic of the EGF-like protein family. DLK2 shares nearly identical structural features with DLK, suggesting that it may function in a similar way. Like DLK, DLK2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells, yet it does so in an opposite way to that of DLK. Also, expression of DLK and DLK2 are inversely correlated and changes in expression of one gene will affect the expression levels of the other. Therefore, it is likely that adipogenesis is modulated by the coordinated expression of DLK and DLK2. There are two isoforms of DLK2 that are produced as a result of alternative splicing events. Function: Regulates adipogenesis. Subcellular Location: Membrane. Similarity: Contains 6 EGF-like domains. SWISS: Q6UY11 Gene ID: 65989 Database links: Entrez Gene: 65989 Human Entrez Gene: 106565 Mouse SwissProt: Q6UY11 Human SwissProt: Q8K1E3 Mouse Unigene: 337251 Human Unigene: 23633 Mouse |
