| 產(chǎn)品編號 | bs-15412R |
| 英文名稱 | HAPLN4 Rabbit pAb |
| 中文名稱 | 透明質(zhì)酸及粘蛋白4抗體 |
| 別 名 | Brain link protein 2; BRAL 2; BRAL2; HAPLN 4; Hapln4; HPLN4_HUMAN; Hyaluronan and proteoglycan link protein 4; Hyaluronan and proteoglycan link protein 4 precursor; KIAA1926. |
| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 細(xì)菌及病毒 細(xì)胞外基質(zhì) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 40 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HAPLN4: 21-120/402 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
HAPLN4 is a 360 amino acid protein encoded by the human gene HAPLN4. HAPLN4 belongs to the HAPLN family and contains 1 Ig-like C2-type (immunoglobulin-like) domain and two Link domains. HAPLN4 mediates the binding of complexes containing hyaluronic acid. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN4 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN4 may also be involved in the formation of extracellular matrices contributing to perineuronal nets and facilitate the understanding of a functional role of these extracellular matrices. HAPLN4 is widely expressed with highest levels in spleen and placenta. Function: Binds to hyaluronic acid and may be involved in formation of the extracellular matrix (By similarity). Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Expressed predominantly in brain. Similarity: Belongs to the HAPLN family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 2 Link domains. SWISS: Q86UW8 Gene ID: 404037 Database links: Entrez Gene: 404037 Human Entrez Gene: 330790 Mouse SwissProt: Q86UW8 Human SwissProt: Q80WM4 Mouse Unigene: 367829 Human Unigene: 152048 Mouse |
