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5HT5A receptor Rabbit pAb (bs-12055R)  
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產(chǎn)品編號 bs-12055R
英文名稱 5HT5A receptor Rabbit pAb
中文名稱 5-羥色胺受體5A抗體
別    名 SR-5A; HTR5A; 5 HT 5A; 5 hydroxytryptamine 5A receptor; 5-HT-5; 5-HT-5A; 5-HT5A; 5-hydroxytryptamine receptor 5A; 5HT5A; 5HT5A_HUMAN; HTR5A; Serotonin receptor 5A.  
研究領(lǐng)域 神經(jīng)生物學(xué)  細(xì)胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT5A receptor/SR-5A: 1-110/357 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P47898

Gene ID:
3361

Database links:

Entrez Gene: 3361 Human

Entrez Gene: 15563 Mouse

Entrez Gene: 25689 Rat

Omim: 601305 Human

SwissProt: P47898 Human

SwissProt: P30966 Mouse

SwissProt: P35364 Rat

Unigene: 65791 Human

Unigene: 4835 Mouse

Unigene: 10569 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Spinal cord tissue lysates Lane 4: Rat Cerebellum tissue lysates Primary: Anti-5HT5A receptor (bs-12055R) at 1/1000 dilution Secondary: IRDye800CW Goat
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Anti
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