| 產品編號 | bs-11695R |
| 英文名稱 | HAAO Rabbit pAb |
| 中文名稱 | 3-羥氨苯甲酸雙加氧酶抗體 |
| 別 名 | 3 HAO; 3 hydroxyanthranilate 3 4 dioxygenase; 3 hydroxyanthranilate dioxygenase; 3 hydroxyanthranilate oxygenase; 3 hydroxyanthranilic acid dioxygenase; 3-HAO; 3-hydroxyanthranilate 3; 3-hydroxyanthranilate 3, 4-dioxygenase; 3-hydroxyanthranilate oxygenas |
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Specific References (1) | bs-11695R has been referenced in 1 publications.
[IF=3.333] Sami Alzarea. et al. The Effect of an α-7 Nicotinic Allosteric Modulator PNU120596 and NMDA Receptor Antagonist Memantine on Depressive-like Behavior Induced by LPS in Mice: The Involvement of Brain Microglia. BRAIN SCI. 2022 Nov;12(11):1493 IF ; Mouse.
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| 研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 信號轉導 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow) |
| 產品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HAAO: 101-200/286 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4. Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. Subcellular Location: Cytoplasm. Similarity: Belongs to the 3-HAO family. SWISS: P46952 Gene ID: 23498 Database links: Entrez Gene: 23498 Human Entrez Gene: 107766 Mouse Omim: 604521 Human SwissProt: P46952 Human SwissProt: Q78JT3 Mouse Unigene: 368805 Human Unigene: 30100 Mouse Unigene: 48675 Rat |
| 產品圖片 |
Sample: Liver (Mouse) Lysate at 40 ug
Primary: Anti-HAAO (bs-11695R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 33 kD
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- HAAO (bs-11695R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 30 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
