產(chǎn)品編號(hào) | bs-11004R |
英文名稱 | FAM63A Rabbit pAb |
中文名稱 | FAM63A蛋白抗體 |
別 名 | FA63A_HUMAN; FAM 63A; FAM63A; Family with sequence similarity 63 member A; FLJ11280; FLJ43504; Hypothetical protein LOC55793; KIAA1390; Protein FAM63A. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52 kDa |
檢測分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FAM63A: 151-250/469 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM63A gene product has been provisionally designated FAM63A pending further characterization. Similarity: Belongs to the FAM63 family. SWISS: Q8N5J2 Gene ID: 55793 Database links: Entrez Gene: 55793 Human Entrez Gene: 75007 Mouse SwissProt: Q8N5J2 Human SwissProt: Q76LS9 Mouse Unigene: 743952 Human Unigene: 279287 Mouse |
產(chǎn)品圖片 |
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-FAM63A (bs-11004R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Sample:
TT(Human) Cell Lysate at 30 ug
Primary: Anti-FAM63A (bs-11004R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Muscle tissue lysates
Lane 3: Rat Cerebrum tissue lysates
Lane 4: Rat Muscle tissue lysates
Primary: Anti-FAM63A (bs-11004R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa
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