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EAF2 Rabbit pAb (bs-7661R)  
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產(chǎn)品編號 bs-7661R
英文名稱 EAF2 Rabbit pAb
中文名稱 睪酮調(diào)節(jié)細(xì)胞凋亡誘導(dǎo)和腫瘤抑制基因抗體
別    名 BM 040; BM040; EAF 2; EAF2; EAF2_HUMAN; Ehrlich S II transcriptional activator factor; ELL Associated Factor 2; ELL-associated factor 2; Festa; Testosterone regulated apoptosis inducer and tumor suppressor; Testosterone Regulated Apoptosis Inducer And Tum  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  細(xì)胞周期蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EAF2: 65-160/260 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.


Function:
Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.

Subunit:
Isoform 1 and isoform 2 interact with TCEA1. Interacts with ELL and ELL2.

Subcellular Location:
Nucleus speckle.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes.

Similarity:
Belongs to the EAF family.

SWISS:
Q96CJ1

Gene ID:
55840

Database links:

Entrez Gene: 55840 Human

Entrez Gene: 106389 Mouse

Entrez Gene: 266787 Rat

Omim: 607659 Human

SwissProt: Q96CJ1 Human

SwissProt: Q91ZD6 Mouse

SwissProt: Q811X5 Rat

Unigene: 477325 Human

Unigene: 432078 Mouse

Unigene: 20681 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EAF2) Polyclonal Antibody, Unconjugated (bs-7661R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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