產(chǎn)品編號(hào) | bs-6325R |
英文名稱(chēng) | GLUT10 Rabbit pAb |
中文名稱(chēng) | 葡萄糖轉(zhuǎn)運(yùn)蛋白10抗體 |
別 名 | facilitated glucose transporter member 10; Glucose Transporter GLUT10; AA450473; Glucose transporter type 10; glut 10; GLUT10; GLUT-10; GTR10_HUMAN; MGC126706; SLC2A10; Solute carrier family 2; Solute carrier family 2, facilitated glucose transporter member 10. |
研究領(lǐng)域 | 心血管 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 糖尿病 轉(zhuǎn)運(yùn)蛋白 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow,Dog) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 67 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GLUT10: 288-335/541 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries. Function: Facilitative glucose transporter. Subcellular Location: Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Tissue Specificity: Widely expressed; highest levels in liver and pancreas. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. SWISS: O95528 Gene ID: 81031 Database links: UniProtKB/Swiss-Prot: O95528.2 |
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