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PDLIM1 Rabbit pAb (bs-2345R)  
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產(chǎn)品編號(hào) bs-2345R
英文名稱 PDLIM1 Rabbit pAb
中文名稱 細(xì)胞骨架蛋白C端PDLIM1抗體
別    名 C terminal LIM domain protein 1; C-terminal LIM domain protein 1; Carboxy terminal LIM domain protein 1; CLIM 1; CLIM1; CLP 36; CLP36; Elfin; Enigma; Enigma homolog; hCLIM 1; hCLIM1; LIM domain protein CLP 36; LIM domain protein CLP-36; LIM domain protein CLP36; PDLI1_HUMAN; PDLIM 1; Pdlim1; PDZ and LIM domain 1; PDZ and LIM domain protein 1.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  新陳代謝  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 36 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDLIM1: 251-329/329 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 PDLIM1 is a cytoskeletal protein that may act as an adapter that brings other proteins to the cytoskeleton. PDLIM1 is strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung, and minimally expressed in liver, thymus, kidney, prostate and pancreas.
It is not found in the brain, testis, ovary, and peripheral blood leukocytes.

Function:
Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.

Subunit:
Interacts with alpha-actinins 1, 2 and 4.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the actin stress fibers.

Tissue Specificity:
Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.

Similarity:
Contains 1 LIM zinc-binding domain.
Contains 1 PDZ (DHR) domain.

SWISS:
O00151

Gene ID:
9124

Database links:

Entrez Gene: 9124 Human

Entrez Gene: 54132 Mouse

Entrez Gene: 54133 Rat

Omim: 605900 Human

SwissProt: O00151 Human

SwissProt: O70400 Mouse

SwissProt: Q3TZ17 Mouse

SwissProt: P52944 Rat

Unigene: 368525 Human

Unigene: 5567 Mouse

Unigene: 11170 Rat



產(chǎn)品圖片
Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti- PDLIM1 (bs-2345R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 36 kD Observed band size: 36 kD
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