| 產(chǎn)品編號 | bs-1953R |
| 英文名稱 | VPS18 Rabbit pAb |
| 中文名稱 | 空泡分選蛋白18抗體 |
| 別 名 | vacuolar protein sorting protein 18; PEP3; VPS18; KIAA1475; hVPS18; Vacuolar protein sorting 18; Vacuolar protein sorting-associated protein 18; vps18; VPS18_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 細(xì)胞周期蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 107 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VPS18: 701-800/973 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Subunit: Interacts with HOOK1. Part of a large heterooligomeric complex together with VPS11, VPS16 and VPS33A. Interacts with STX7. Subcellular Location: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes. Tissue Specificity: Ubiquitous. Expression was highest in heart and low in lung. Similarity: Belongs to the VPS18 family. Contains 1 clathrin repeat. Contains 1 RING-type zinc finger. SWISS: Q9P253 Gene ID: 57617 Database links: Entrez Gene: 57617 Human Entrez Gene: 228545 Mouse Omim: 608551 Human SwissProt: Q9P253 Human SwissProt: Q8R307 Mouse Unigene: 23876 Human Unigene: 294761 Mouse |
