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Parvalbumin Rabbit pAb (bs-1299R)  
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產(chǎn)品編號 bs-1299R
英文名稱 Parvalbumin Rabbit pAb
中文名稱 細(xì)小清蛋白抗體
別    名 D22S749; MGC116759; Parvalbumin alpha; PRVA_HUMAN; PVALB.  
Specific References  (2)     |     bs-1299R has been referenced in 2 publications.
[IF=2.21] Qi et al. Interaction of basolateral amygdala, ventral hippocampus and medial prefrontal cortex regulates the consolidation and extinction of social fear. (2018) Behav.Brain.Funct. 14:7  other ;  Mouse.  
[IF=1.68] Chen J et al. Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study.J Ophthalmol. 2019 Mar 3;2019:7089342.  IF ;  Monkey.  
研究領(lǐng)域 神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig,Cow,Chicken,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞外基質(zhì) 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Parvalbumin: 7-110/110 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Belongs to the parvalbumin family. Contains 2 EF-hand domains. This protein binds two calcium ions.

Function:
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

Similarity:
Belongs to the parvalbumin family.
Contains 2 EF-hand domains.

SWISS:
P20472

Gene ID:
5816

Database links:

Entrez Gene: 396459 Chicken

Entrez Gene: 396531 Chicken

Entrez Gene: 5816 Human

Entrez Gene: 19293 Mouse

Entrez Gene: 25269 Rat

Omim: 168890 Human

SwissProt: P20472 Human

SwissProt: P32848 Mouse

SwissProt: P02625 Rat

Unigene: 295449 Human

Unigene: 2766 Mouse

Unigene: 2005 Rat



(Parvalbumin, PV)細(xì)小白蛋白屬于鈣結(jié)合蛋白家族,是一種細(xì)胞內(nèi)可溶的小結(jié)合蛋白,過去曾認(rèn)為,僅出現(xiàn)在哺乳動物某些肌纖維內(nèi),它與Ca2+有高度親合力,與鈣調(diào)蛋白競爭自由Ca2+,故可阻止肌漿內(nèi)的Ca2+增高,可抗衡細(xì)胞內(nèi)鈣過量的發(fā)生。
產(chǎn)品圖片
Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Rat Kidney tissue lysates Primary: Anti-Parvalbumin (bs-1299R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12 kDa Observed band size: 10 kDa
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Parvalbumin) Polyclonal Antibody, Unconjugated (bs-1299R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Parvalbumin) Polyclonal Antibody, Unconjugated (bs-1299R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
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